CCNA1 Promoter Methylation: a Potential Marker for Grading Papanicolaou Smear Cervical Squamous Intraepithelial Lesions
نویسندگان
چکیده
منابع مشابه
CCNA1 Promoter Methylation: A Potential Marker for Grading Papanicolaou Smear CIN Lesions
Cervical cancer is the second most common type of cancer in women in less developed country. In South-east Asia regions, there was 51,000 newly diagnosed case and 24,000 deaths in the year 2012 (GLOBOCAN, 2012). Notably, cervical cancer has the pathological feature of long precancerous phase and spanning years. In both developed and developing countries, the cytology-based method (Pap test) usi...
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Background : We examined cervicovaginal smears that contained definite low-grade squamous intraepithelial lesion (LSIL) cells and rare atypical cells suggestive of high-grade SIL (HSIL) (ASC-H) or contained borderline dysplastic cells between LSIL and HSIL. Such lesions were classified as LSIL-H. This study aimed to investigate the cytologic and histologic characteristics of LSIL-H category and...
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BACKGROUND: Anal smears are increasingly being used as a screening test for anal squamous intraepithelial lesions (ASILs). This study was undertaken to assess the usefulness and limitations of anal smears in screening for ASILs. METHODS: The cytomorphological features of 200 consecutive anal smears collected in liquid medium from 198 patients were studied and findings were correlated with resul...
متن کاملHPV and cervical squamous intraepithelial lesions: clinicopathological study.
The aim of our study is to determine the evidence of HPV infection, by either HPV-DNA test or histopathological examination, in patients with abnormal PAP-smear, for further clinical management. In 6-month period, we retrospectively selected a number of 103 patients in 16-54 years range of age that were investigated by complex diagnostic techniques supporting the evidence of HPV infection. Init...
متن کاملSquamous intraepithelial lesions
C ervical carcinoma is a significant contributor to cancer-related morbidity and mortality worldwide and the role of human papillomavirus (HPV) in the development of preinvasive and invasive cervical lesions is well established. 2 Although significant advances have been made in elucidating the potential mechanisms of cellular transformation by HPV and in the molecular detection of HPV in cytolo...
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ژورنال
عنوان ژورنال: Asian Pacific Journal of Cancer Prevention
سال: 2014
ISSN: 1513-7368
DOI: 10.7314/apjcp.2014.15.18.7971